Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404198 | 1.00 | EPHX2 (0.40) | EPHX2TSHRNOS2 | |
| SCHEMBL749590 | 1.00 | EPHX2 (0.40) | EPHX2TSHRNOS2 | |
| SCHEMBL5660 | 0.87 | — | — | |
| SCHEMBL11702505 | 0.79 | NOS2 (0.32) | NOS2 | |
| SCHEMBL10437831 | 0.78 | CES2 (0.38) | EPHX2TSHR | |
| SCHEMBL217137 | 0.75 | — | — | |
| SCHEMBL216556 | 0.75 | — | — | |
| SCHEMBL27898083 | 0.75 | CHRNB2 (0.44) | EPHX2TSHR | |
| SCHEMBL7069140 | 0.75 | CHRNB2 (0.44) | EPHX2TSHR | |
| SCHEMBL754013 | 0.74 | NOS2 (0.35) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439174-B1 | 4-IMIDAZOLIN-2-ONE COMPOUNDS AS p38 MAP KINASE INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |