Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL3093695 | 0.94 | SMN1; SMN2 (0.48) | LMNAPOLBALDH1A1PDK1SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL11791402 | 0.89 | LMNA (0.50) | LMNAPOLBALDH1A1PDK1SMN1; SMN2 | |
| SCHEMBL812840 | 0.89 | LMNA (0.52) | LMNAPOLBALDH1A1SMN1; SMN2KMT2A | |
| Alcohol SCHEMBL20394646 | 0.87 | SMN1; SMN2 (0.59) | LMNAPOLBALDH1A1PDK1SMN1; SMN2 | |
| SCHEMBL3757540 | 0.87 | LMNA (0.50) | LMNAPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL16345225 | 0.87 | LMNA (0.50) | LMNAPOLBALDH1A1SMN1; SMN2PRMT5 | |
| Barium SCHEMBL2592652 | 0.87 | LMNA (0.50) | LMNAPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6291878 | 0.85 | — | — | |
| SCHEMBL1002690 | 0.85 | — | — | |
| SCHEMBL26039174 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-215517224-U | Refining system of tetrahydrofurfuryl alcohol ether crude | 新疆昱华石油化工有限公司 | 2022-01-14 | — | — | CN | claimed |
| CN-113683586-A | Refining method and refining system for tetrahydrofurfuryl alcohol ethyl ether crude product | 新疆昱华石油化工有限公司 | 2021-11-23 | — | — | CN | claimed |
| CN-109206568-B | SBS containing 1,2 structure uniformly distributed butadiene block and hydride thereof, preparation and application method | 中国石油化工股份有限公司 | 2021-09-03 | — | — | CN | claimed |
| CN-109575189-B | Monovinylarene-conjugated diene polymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-112480341-A | Branched polystyrene-b-conjugated diene diblock copolymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-111777729-A | Wide-distribution, high-elasticity and functionalized solution-polymerized styrene-butadiene rubber, preparation method thereof and application thereof in tire tread rubber | 中国石油化工股份有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-210885884-U | Device for recycling bromine element in industrial production of tetrahydrofurfuryl alcohol ether | 朱荣辉 | 2020-06-30 | — | — | CN | claimed |
| CN-107556416-B | Liquid polyisoprene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-107556415-B | Liquid poly-conjugated diene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-110627751-A | Device and method for recycling bromine element in industrial production of tetrahydrofurfuryl alcohol ether | 朱荣辉 | 2019-12-31 | — | — | CN | claimed |
| CN-102558441-A | Synthetic method of solution polymerized butadiene-isoprene rubber | CHINA PETROLEUM & CHEMICAL | 2012-07-11 | — | — | CN | claimed |
| CN-102558465-A | Synthesizing method of solution polymerized styrene butadiene rubber | CHINA PETROLEUM & CHEMICAL | 2012-07-11 | — | — | CN | claimed |
| CN-102453305-A | Monovinylarene and conjugated diene block copolymer composition, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2012-05-16 | — | — | CN | claimed |
| CN-102453303-A | Monovinylarene-conjugated diene block copolymer composition and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2012-05-16 | — | — | CN | claimed |
| CN-102453304-A | Monovinylarene-conjugated diene block copolymer composition and preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2012-05-16 | — | — | CN | claimed |
| CN-102234357-A | Linear butadiene styrene copolymer material for sealing strip, its preparation and application | CHINA PETROCHEMICAL CORP | 2011-11-09 | — | — | CN | claimed |
| CN-102234358-A | Star styrene-butadiene-styrene (SBS) copolymer for sealing strip as well as preparation and application thereof | CHINA PETROCHEMICAL CORP | 2011-11-09 | — | — | CN | claimed |
| CN-102108114-A | Impact-resistant transparent linear asymmetric block copolymer of vinyl aromatic hydrocarbon and conjugated diene and preparation method of block copolymer | CHINA PETROLEUM & CHEMICAL | 2011-06-29 | — | — | CN | claimed |
| CN-102101902-A | Method for preparing irregular copolymer of conjugated diene and vinyl arene | CHINA PETROLEUM & CHEMICAL | 2011-06-22 | — | — | CN | claimed |
| CN-101817911-A | Star block copolymer prepared from isoprene, butadiene and styrene, and preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2010-09-01 | — | — | CN | claimed |