Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL7527792 | 0.94 | LMNA (0.49) | SMN1; SMN2ALDH1A1TDP1LMNAPOLB | |
| SCHEMBL594011 | 0.90 | TSHR (0.54) | SMN1; SMN2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL3093708 | 0.87 | TSHR (0.47) | SMN1; SMN2ALDH1A1TDP1TSHRLMNA | |
| Ethylene Glycol SCHEMBL11791402 | 0.84 | LMNA (0.50) | SMN1; SMN2ALDH1A1TSHRLMNAPOLB | |
| Alcohol SCHEMBL150777 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL812840 | 0.84 | LMNA (0.52) | SMN1; SMN2ALDH1A1TSHRLMNAPOLB | |
| Alcohol SCHEMBL20394646 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL16345225 | 0.82 | LMNA (0.50) | SMN1; SMN2ALDH1A1TSHRLMNAPOLB | |
| Barium SCHEMBL2592652 | 0.82 | LMNA (0.50) | SMN1; SMN2ALDH1A1TSHRLMNAPOLB | |
| SCHEMBL3757540 | 0.82 | LMNA (0.50) | SMN1; SMN2ALDH1A1TSHRLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987233-A | Cationic UV (ultraviolet) heat curing composition and preparation method thereof | 上海汉司实业有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-110582540-B | Photocurable epoxy composition | 汉高股份有限及两合公司 | 2022-11-22 | — | — | CN | claimed |
| CN-110582540-A | Photocurable epoxy composition | 汉高股份有限及两合公司 | 2019-12-17 | — | — | CN | claimed |
| WO-2018184151-A1 | Light cure epoxy composition | HENKEL AG & CO. KGAA (DE) | 2018-10-11 | — | — | WO | claimed |
| CN-116987233-A | Cationic UV (ultraviolet) heat curing composition and preparation method thereof | 上海汉司实业有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-110582540-B | Photocurable epoxy composition | 汉高股份有限及两合公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-110582540-A | Photocurable epoxy composition | 汉高股份有限及两合公司 | 2019-12-17 | — | — | CN | disclosed |
| WO-2018184151-A1 | Light cure epoxy composition | HENKEL AG & CO. KGAA (DE) | 2018-10-11 | — | — | WO | disclosed |
| EP-2640765-B1 | ONE COMPONENT EPOXY RESIN COMPOSITION | Henkel IP & Holding GmbH (DE) | 2017-01-04 | — | — | EP | disclosed |
| CN-103333329-B | Method for preparing polycarbonate by copolymerizing carbon dioxide and alpha-pinene derivatives | UNIV KUNMING SCIENCE & TECHNOLOGY | 2015-06-03 | — | — | CN | disclosed |
| EP-2867270-A1 | WATER-BASED EPOXY RESIN EMULSION | Henkel AG & Co. KGaA (DE) | 2015-05-06 | — | — | EP | disclosed |
| WO-2014104380-A1 | AQUEOUS AMINE EMULSION | HENKEL AG & CO. KGAA (DE) | 2014-07-03 | — | — | WO | disclosed |
| WO-2012067270-A1 | ONE COMPONENT EPOXY RESIN COMPOSITION | HENKEL JAPAN LTD. (JP) | 2012-05-24 | — | — | WO | disclosed |
| US-7795744-B2 | Cationically curable epoxy resin composition | HENKEL CORPORATION (US) | 2010-09-14 | — | — | US | disclosed |
| CN-101676315-A | Sealant for liquid crystal instillation technique and method for manufacturing liquid crystal dispaly | HENKEL CORP | 2010-03-24 | — | — | CN | disclosed |
| US-7456230-B2 | Cationically photocurable epoxy resin compositions | HENKEL CORPORATION (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070208106-A1 | Cationically Curable Epoxy Resin Composition | Henkel IP & Holding GmbH (DE) | 2007-09-06 | — | — | US | disclosed |
| CN-1288207-C | Photocationic curable epoxy resin composition | HENKEL LOCTITE CORP (US) | 2006-12-06 | — | — | CN | disclosed |
| US-20050245643-A1 | Photo-induced cation curable epoxy resin composition | Henkel IP & Holding GmbH (DE) | 2005-11-03 | — | — | US | disclosed |
| CN-1665881-A | Photocationic curable epoxy resin composition | HENKEL LOCTITE CORP (US) | 2005-09-07 | — | — | CN | disclosed |