Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17477726 | 0.86 | KIF11 (0.50) | KIF11AKR1C3AKR1C2HTTADORA2A | |
| SCHEMBL7524850 | 0.79 | IDO1 (0.47) | RAPGEF4 | |
| SCHEMBL17477740 | 0.78 | KIF11 (0.47) | KIF11AKR1C3AKR1C2HTTIDH2 | |
| SCHEMBL15913218 | 0.77 | KIF11 (0.53) | KIF11AKR1C3AKR1C2ADORA2AIDH2 | |
| SCHEMBL7519427 | 0.75 | GRM4 (0.44) | RAPGEF4 | |
| SCHEMBL7559638 | 0.74 | KIF11 (0.53) | KIF11ADORA2AIDH2DHODHRAPGEF4 | |
| SCHEMBL15992074 | 0.74 | KIF11 (0.52) | KIF11ADORA2AIDH2DHODHRAPGEF4 | |
| SCHEMBL7520161 | 0.74 | KIF11 (0.52) | KIF11AKR1C3AKR1C2HTTADORA2A | |
| SCHEMBL394991 | 0.74 | KIF11 (0.70) | KIF11AKR1C3AKR1C2HTTADORA2A | |
| SCHEMBL15913806 | 0.72 | ALDH1A1 (0.47) | KIF11HTTADORA2AIDH2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |