Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4220779 | 0.84 | TSHR (0.52) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11835914 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7529721 | 0.79 | LMNA (0.54) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7530814 | 0.79 | MEN1 (0.54) | MEN1RAB9AKMT2ANPC1MAPT | |
| SCHEMBL2819135 | 0.79 | KMT2A (0.60) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL12217636 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11144767 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL19073479 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL20482299 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9479110 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |