Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4220779 | 0.84 | TSHR (0.52) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL7528435 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2AMAPTLMNAATM | |
| SCHEMBL7529721 | 0.79 | LMNA (0.54) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL25244989 | 0.79 | MEN1 (0.56) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL11876453 | 0.79 | VCAM1 (0.58) | MEN1KMT2AMAPTLMNAGAA | |
| Hydrochloric Acid SCHEMBL27825662 | 0.77 | VCAM1 (0.57) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL7530821 | 0.76 | VCAM1 (0.62) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL9820882 | 0.76 | MEN1 (0.54) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL5187322 | 0.76 | MEN1 (0.85) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL2095962 | 0.75 | EPHX1 (0.52) | MEN1KMT2AMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |