Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530814 | 0.84 | MEN1 (0.54) | HTTMAPK1ATMMAPTMEN1 | |
| SCHEMBL7529721 | 0.84 | LMNA (0.54) | HTTALDH1A1MAPK1MAPTMEN1 | |
| SCHEMBL7528435 | 0.84 | ALDH1A1 (0.55) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL29702837 | 0.76 | TSHR (0.50) | TSHRCYP3A4CASP6HTTALDH1A1 | |
| SCHEMBL27039902 | 0.76 | ALDH1A1 (0.55) | TSHRCYP3A4CASP6HTTALDH1A1 | |
| SCHEMBL28165237 | 0.76 | TSHR (0.50) | TSHRCYP3A4CASP6HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28375819 | 0.74 | TSHR (0.48) | TSHRCYP3A4CASP6HTTALDH1A1 | |
| SCHEMBL1486315 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL4220780 | 0.73 | TSHR (0.47) | TSHRCYP3A4CASP6HTTALDH1A1 | |
| SCHEMBL225468 | 0.72 | KMT2A (0.59) | TSHRHTTALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215839-A1 | SYDNONIMINES-SPECIFIC DOPAMINE REUPTAKE INHIBITORS AND THEIR USE IN TREATING DOPAMINE RELATED DISORDERS | CHEN HAO | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215839-A1 | SYDNONIMINES-SPECIFIC DOPAMINE REUPTAKE INHIBITORS AND THEIR USE IN TREATING DOPAMINE RELATED DISORDERS | SLC6A3, SLC18A2, SLC6A2 | TSHR 1029/4885CYP3A4 3566/4885CASP6 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.