SCHEMBL752853

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754214	0.88	LIPG (0.45)	LIPGRXRBHRH3ALDH1A1HTT
	SCHEMBL753023	0.85	HRH3 (0.41)	LIPGOXTRAVPR1ARXRBHRH3
	SCHEMBL754428	0.84	LIPG (0.48)	LIPGACACB
	SCHEMBL752750	0.82	NPC1 (0.50)	LIPGGPR84ALDH1A1NPC1RAB9A
	SCHEMBL753739	0.81	LIPG (0.43)	LIPGHRH3GPR84EGLN1KMT2A
	SCHEMBL754703	0.79	LIPG (0.47)	LIPGHRH3ALDH1A1EGLN1KMT2A
	SCHEMBL2486824	0.74	HRH3 (0.43)	LIPGRXRBHRH3ALDH1A1HTT
	SCHEMBL752971	0.73	LIPG (0.49)	LIPGHRH3ALDH1A1EGLN1
	SCHEMBL754174	0.70	LIPG (0.46)	LIPGHRH3ALDH1A1EGLN1KMT2A
	SCHEMBL11381193	0.69	LIPG (0.47)	LIPGKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.