SCHEMBL752750

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755973	0.84	PKM (0.41)	LIPGALDH1A1MAPK1
	SCHEMBL752853	0.82	LIPG (0.42)	NPC1RAB9ACYP1A2CYP2C19LIPG
	SCHEMBL753739	0.81	LIPG (0.43)	LIPGGPR84
	SCHEMBL754428	0.78	LIPG (0.48)	LIPGL3MBTL1
	SCHEMBL754930	0.78	GPR84 (0.38)	NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19
	SCHEMBL754125	0.76	LIPG (0.33)	LIPG
	SCHEMBL752280	0.75	LIPG (0.45)	LIPGALDH1A1MAP2K7
	SCHEMBL754703	0.75	LIPG (0.47)	CYP1A2CYP2C19LIPGL3MBTL1ALDH1A1
	SCHEMBL753011	0.75	JAK2 (0.45)	LIPGL3MBTL1RECQLMAPK1TDP1
	SCHEMBL756752	0.73	KMO (0.49)	SMN1; SMN2CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.