SCHEMBL754703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755290	0.87	LIPG (0.50)	LIPGALDH1A1HRH3EGLN1
	SCHEMBL754428	0.85	LIPG (0.48)	LIPGPOLBL3MBTL1
	SCHEMBL755270	0.84	HRH3 (0.38)	LIPGALKBH1MEN1KMT2AGRM5
	SCHEMBL752853	0.79	LIPG (0.42)	LIPGKMT2APLA2G7ALDH1A1CYP1A2
	SCHEMBL752750	0.75	NPC1 (0.50)	LIPGL3MBTL1ALDH1A1CYP1A2CYP2C19
	SCHEMBL753739	0.74	LIPG (0.43)	LIPGMEN1KMT2APLA2G7HRH3
	SCHEMBL752971	0.73	LIPG (0.49)	LIPGALDH1A1HRH3EGLN1
	SCHEMBL2485979	0.73	PIM1 (0.43)	LIPGALKBH1MEN1KMT2APOLB
	SCHEMBL11381193	0.72	LIPG (0.47)	LIPGKMT2A
	SCHEMBL757191	0.72	HRH3 (0.40)	LIPGL3MBTL1ALDH1A1HRH3EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.