Phosphoric Acid

Phosphoric Acid

SCHEMBL7528671

O=P([O-])(O)O.O=P([O-])(O)O.O=P([O-])([O-])[O-].[K+].[K+].[Na+].[Na+].[Na+]

nearest known ligand 0.82

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.82
KDM4E B2RXH2 2/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 2/20 0.44
CA4 P22748 3/20 0.36
CA2 P00918 1/20 0.36
FAHD1 Q6P587 1/20 0.36
TYMS P04818 1/20 0.35
CA1 P00915 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
FDPS P14324 2/20 0.33
MMP2 P08253 2/20 0.33
MMP1 P03956 1/20 0.33
THRB P10828 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL6310117 1.00 SLC34A1 (0.82) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL5745536 1.00 SLC34A1 (0.82) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL27544253 1.00 SLC34A1 (0.82) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL2128094 1.00 SLC34A1 (0.82) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL7623899 0.96 SLC34A1 (0.75) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL2954685 0.95 SLC34A1 (0.90) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL7530569 0.95 SLC34A1 (0.90) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL10787868 0.95 SLC34A1 (0.90) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL5293558 0.95 SLC34A1 (0.90) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL5907878 0.95 SLC34A1 (0.90) SLC34A1KDM4ECYP2C19KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3472137-A1 PROCESS FOR PREPARING ATALUREN AND ITS INTERMEDIATES ScinoPharm Taiwan, Ltd. (TW) 2019-04-24 EP claimed
US-10138215-B2 Process for preparing ataluren and its intermediates SCINOPHARM TAIWAN, LTD. (TW) 2018-11-27 US claimed
WO-2017222474-A1 PROCESS FOR PREPARING ATALUREN AND ITS INTERMEDIATES SCINOPHARM TAIWAN, LTD. (TW) 2017-12-28 WO claimed
US-20170362192-A1 PROCESS FOR PREPARING ATALUREN AND ITS INTERMEDIATES SCINOPHARM TAIWAN, LTD. (TW) 2017-12-21 US claimed
EP-2822929-B1 PROCESS FOR PREPARATION OF ROFLUMILAST SCINOPHARM (CHANGSHU) PHARMACEUTICALS LTD (CN) 2017-06-14 EP claimed
US-9085533-B2 Process for preparation of roflumilast SCINOPHARM (CHANGSHU) PHARMACEUTICALS, LTD. (CN) 2015-07-21 US claimed
US-20150025246-A1 PROCESS FOR PREPARATION OF ROFLUMILAST SCINOPHARM (CHANGSHU) PHARMACEUTICALS, LTD. (CN) 2015-01-22 US claimed
EP-2822929-A1 PROCESS FOR PREPARATION OF ROFLUMILAST Scinopharm (Changshu) Pharmaceuticals Ltd. (CN) 2015-01-14 EP claimed
WO-2013131484-A1 PROCESS FOR PREPARATION OF ROFLUMILAST SCINOPHARM (CHANGSHU) PHARMACEUTICAL, LTD. (CN) 2013-09-12 WO claimed
CN-117642428-A Antibodies to UCB生物制药有限责任公司 2024-03-01 CN disclosed
EP-3472137-A1 PROCESS FOR PREPARING ATALUREN AND ITS INTERMEDIATES ScinoPharm Taiwan, Ltd. (TW) 2019-04-24 EP disclosed
US-10138215-B2 Process for preparing ataluren and its intermediates SCINOPHARM TAIWAN, LTD. (TW) 2018-11-27 US disclosed
WO-2017222474-A1 PROCESS FOR PREPARING ATALUREN AND ITS INTERMEDIATES SCINOPHARM TAIWAN, LTD. (TW) 2017-12-28 WO disclosed
US-20170362192-A1 PROCESS FOR PREPARING ATALUREN AND ITS INTERMEDIATES SCINOPHARM TAIWAN, LTD. (TW) 2017-12-21 US disclosed
US-20150025246-A1 PROCESS FOR PREPARATION OF ROFLUMILAST SCINOPHARM (CHANGSHU) PHARMACEUTICALS, LTD. (CN) 2015-01-22 US disclosed
EP-2822929-A1 PROCESS FOR PREPARATION OF ROFLUMILAST Scinopharm (Changshu) Pharmaceuticals Ltd. (CN) 2015-01-14 EP disclosed
WO-2013131484-A1 PROCESS FOR PREPARATION OF ROFLUMILAST SCINOPHARM (CHANGSHU) PHARMACEUTICAL, LTD. (CN) 2013-09-12 WO disclosed
EP-0851224-B1 Biosensor with C-shaped counter electrode MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2002-03-27 EP disclosed
US-5985116-A Biosensor MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-11-16 US disclosed
EP-0851224-A1 Biosensor with C-shaped counter electrode MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150025246-A1 PROCESS FOR PREPARATION OF ROFLUMILAST REN, CYP3A5, CYP2C19 SLC34A1 3965/4885KDM4E 507/4885CYP2C19 3/4885
US-20170362192-A1 PROCESS FOR PREPARING ATALUREN AND ITS INTERMEDIATES AGT, AGTR1, GRHPR SLC34A1 2440/4885KDM4E 1858/4885CYP2C19 143/4885
US-10138215-B2 Process for preparing ataluren and its intermediates AGT, AGTR1, GRHPR SLC34A1 2440/4885KDM4E 1858/4885CYP2C19 143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.