Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988597 | 0.99 | LMNA (0.74) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4661580 | 0.89 | LMNA (0.71) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4660272 | 0.88 | LMNA (0.70) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4660398 | 0.87 | LMNA (0.68) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4662887 | 0.86 | LMNA (0.71) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL7529105 | 0.86 | LMNA (0.57) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4661617 | 0.86 | LMNA (0.67) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4661746 | 0.86 | LMNA (0.67) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4660309 | 0.86 | LMNA (0.67) | LMNAMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4661735 | 0.86 | LMNA (0.67) | LMNAMAPTALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020041889-A1 | ENHANCING AGENT FOR DEGRADATION OF DESMOSOMES OR STRATUM CORNEUM DESQUAMATION | SHISEIDO COMPANY, LTD. (JP) | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020041889-A1 | ENHANCING AGENT FOR DEGRADATION OF DESMOSOMES OR STRATUM CORNEUM DESQUAMATION | DSG1, DSC1, CUTA | LMNA 1600/4885MAPT 2346/4885ALDH1A1 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.