Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118884 | 0.86 | MAPK1 (0.37) | ALDH1A1HTTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL2954086 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HTTLMNAMAPK1PDE4D | |
| SCHEMBL7052453 | 0.82 | USP2 (0.40) | ALDH1A1HTTMAPK1SMN1; SMN2CYP17A1 | |
| SCHEMBL7522491 | 0.82 | PABPC1 (0.50) | ALDH1A1CYP19A1 | |
| SCHEMBL23736419 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HTTLMNAMAPK1PDE4D | |
| SCHEMBL18368418 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HTTLMNAMAPK1PDE4D | |
| SCHEMBL17072863 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTLMNAMAPK1PDE4D | |
| SCHEMBL27558665 | 0.74 | CYP17A1 (0.58) | ALDH1A1HTTLMNAMAPK1PDE4D | |
| SCHEMBL27495104 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HTTLMNAMAPK1PDE4D | |
| SCHEMBL7522328 | 0.73 | MAPT (0.43) | ALDH1A1LMNAMAPK1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137152-A1 | Fermentation process for epothilones | KOSAN BIOSCIENCES, INC. | 2002-09-26 | — | — | US | disclosed |