Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522491 | 0.84 | PABPC1 (0.50) | PABPC1APOBEC3AAPOBEC3GCYP19A1KMT2A | |
| SCHEMBL7529301 | 0.82 | ALDH1A1 (0.46) | MAPK1CYP19A1CYP17A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7522228 | 0.73 | JUN (0.38) | USP2MAPK1CYP19A1MAPTSMN1; SMN2 | |
| SCHEMBL7054847 | 0.73 | JUN (0.38) | USP2MAPK1CYP19A1MAPTSMN1; SMN2 | |
| SCHEMBL9683295 | 0.72 | MAPK1 (0.51) | USP2MAPK1CYP19A1CYP17A1KMT2A | |
| SCHEMBL10516365 | 0.71 | CYP19A1 (0.54) | USP2MAPK1CYP19A1CYP17A1KMT2A | |
| SCHEMBL7515532 | 0.69 | HDAC8 (0.38) | CYP19A1CYP17A1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL7552631 | 0.68 | PABPC1 (0.50) | PABPC1APOBEC3AAPOBEC3GCYP19A1KMT2A | |
| SCHEMBL27504614 | 0.68 | CYP1A2 (0.45) | NPSR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL2208580 | 0.68 | PABPC1 (0.50) | PABPC1APOBEC3AAPOBEC3GCYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303615-A2 | FERMENTATION PROCESS FOR EPOTHILONES | Kosan Biosciences, Inc. (US) | 2003-04-23 | — | — | EP | claimed |
| US-20020137152-A1 | Fermentation process for epothilones | KOSAN BIOSCIENCES, INC. | 2002-09-26 | — | — | US | claimed |
| WO-2002008440-A2 | FERMENTATION PROCESS FOR EPOTHILONES | KOSAN BIOSCIENCES, INC. (US) | 2002-01-31 | — | — | WO | claimed |
| EP-1303615-A2 | FERMENTATION PROCESS FOR EPOTHILONES | Kosan Biosciences, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| US-20020137152-A1 | Fermentation process for epothilones | KOSAN BIOSCIENCES, INC. | 2002-09-26 | — | — | US | disclosed |
| WO-2002008440-A2 | FERMENTATION PROCESS FOR EPOTHILONES | KOSAN BIOSCIENCES, INC. (US) | 2002-01-31 | — | — | WO | disclosed |