Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531036 | 0.77 | HTR6 (0.43) | HTR6ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL6290237 | 0.77 | HTR6 (0.40) | HTR6ALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL6714540 | 0.77 | PSEN1 (0.37) | ALDH1A1MAPTMEN1CYP2D6KMT2A | |
| SCHEMBL6290827 | 0.74 | MAPT (0.55) | HTR6ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL6710676 | 0.73 | SCN9A (0.45) | MEN1CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL7491311 | 0.68 | CHRNB2 (0.39) | ALDH1A1SMN1; SMN2MEN1CYP3A4CYP2D6 | |
| SCHEMBL7492223 | 0.68 | HTT (0.39) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7494214 | 0.67 | SMN1; SMN2 (0.45) | ALDH1A1HPGDMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5870992 | 0.67 | OPRD1 (0.39) | LMNAGAA | |
| SCHEMBL7498243 | 0.67 | OPRD1 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022579-A2 | ANTIPSYCHOTIC SULFONAMIDE-HETEROCYCLES, AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-03-21 | — | — | WO | disclosed |