SCHEMBL7529588

SCHEMBL7529588

C=C(C)C(=O)OCCOCCSc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
ALDH1A1 P00352 8/20 0.45
KDM4E B2RXH2 5/20 0.43
MAPT P10636 3/20 0.42
CYP1A2 P05177 3/20 0.42
CYP2D6 P10635 3/20 0.42
CYP2C19 P33261 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
RECQL P46063 2/20 0.42
CYP3A4 P08684 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8016747 0.92 THRB (0.45) THRBMTNR1AMTNR1BALDH1A1KDM4E
SCHEMBL2392778 0.91 MTNR1A (0.50) THRBMTNR1AMTNR1BALDH1A1KDM4E
SCHEMBL25118380 0.88 THRB (0.50) THRBMTNR1AMTNR1BALDH1A1KDM4E
SCHEMBL25118379 0.88 THRB (0.50) THRBMTNR1AMTNR1BALDH1A1KDM4E
SCHEMBL25119635 0.84 LMNA (0.48) THRBALDH1A1KDM4EMAPTTDP1
SCHEMBL8028273 0.84 TDP1 (0.52) THRBMTNR1AMTNR1BALDH1A1KDM4E
SCHEMBL8028295 0.82 TDP1 (0.55) THRBMTNR1AMTNR1BALDH1A1KDM4E
SCHEMBL285646 0.82 TDP1 (0.55) THRBMTNR1AMTNR1BALDH1A1KDM4E
SCHEMBL25118396 0.81 THRB (0.43) THRBMTNR1AMTNR1BALDH1A1KDM4E
SCHEMBL9159591 0.80 THRB (0.54) THRBALDH1A1TDP1CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP disclosed
US-6206550-B1 BACKLIGHT WITH LENS PORTION MADE FROM A CURABLE COMPOSITION WHICH INCLUDES A BIS(4-(METH)ACRYLOYL-THIOPHENYL) SULFIDE AND (METH)ACRYLATES; HIGH BRIGHTNESS-ENHANCING EFFECT ON LENSES OF PROJECTION TVS AND STEREOSCOPIC PHOTOGRAPHY. MITSUBISHI RAYON COMPANY LTD. (JP) 2001-03-27 US disclosed
EP-0952466-A2 Lens sheet MITSUBISHI RAYON CO., LTD. (JP) 1999-10-27 EP disclosed
US-5969867-A ACRYLIC ESTERS MITSUBISHI RAYON COMPANY LTD. (JP) 1999-10-19 US disclosed
EP-0735062-A1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO., LTD. (JP) 1996-10-02 EP disclosed