SCHEMBL752977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10290647	0.92	ALDH1A1 (0.38)	ALDH1A1LMNAHPGDMEN1KMT2A
	SCHEMBL754834	0.75	CYP1A2 (0.38)	ALDH1A1LMNAHPGDMEN1KMT2A
	SCHEMBL753326	0.75	LIPG (0.46)	ALDH1A1LMNAHPGDTP53HTT
	SCHEMBL13255591	0.72	CYP1A2 (0.38)	ALDH1A1LMNAHPGDMEN1KMT2A
	SCHEMBL752416	0.71	POLB (0.39)	ALDH1A1LMNAHPGDKMT2ASMN1; SMN2
	SCHEMBL764352	0.70	CYP1A2 (0.40)	ALDH1A1LMNAHPGDMEN1KMT2A
	SCHEMBL4676184	0.70	HTT (0.75)	ALDH1A1LMNAHPGDMEN1KMT2A
	SCHEMBL2186229	0.70	MAPT (0.50)	ALDH1A1LMNAHPGDKMT2ASMN1; SMN2
	SCHEMBL3221601	0.68	HTT (0.47)	ALDH1A1LMNAHPGDKMT2ATP53
	SCHEMBL4677310	0.68	HDAC4 (0.54)	ALDH1A1LMNAHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.