Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFSF11 | O14788 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536283 | 0.96 | HMGCR (0.36) | TNFSF11PDE4DPDE3BPDE3ADRD2 | |
| SCHEMBL7531040 | 0.86 | HMGCR (0.38) | PDE4DPDE3BPDE3AHMGCRMTNR1A | |
| SCHEMBL7530400 | 0.85 | MTNR1A (0.36) | PDE4DPDE3BPDE3ADRD2HMGCR | |
| SCHEMBL7530218 | 0.84 | HMGCR (0.41) | PDE4DPDE3BPDE3ADRD2HMGCR | |
| SCHEMBL7532128 | 0.81 | MTNR1B (0.40) | PDE4DMTNR1AMTNR1BTSHR | |
| SCHEMBL8959275 | 0.80 | HMGCR (0.41) | PDE4DHMGCRBACE1 | |
| SCHEMBL7533095 | 0.80 | MTNR1A (0.39) | PDE4DPDE3BPDE3ADRD2MTNR1A | |
| SCHEMBL7536742 | 0.80 | MTNR1A (0.39) | PDE4DPDE3BPDE3ADRD2MTNR1A | |
| SCHEMBL7530080 | 0.80 | MTNR1A (0.39) | PDE4DPDE3BPDE3ADRD2MTNR1A | |
| SCHEMBL7531447 | 0.78 | TNFSF11 (0.46) | TNFSF11PDE4DPDE3BPDE3AHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585371-B1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INTERNAT H (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0585371-A4 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INT (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0585371-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020350-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | disclosed |