SCHEMBL7530238

SCHEMBL7530238

CCO[Si](OCC)(OCC)c1c(C(C)C)ccc(N)c1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1228797 0.68 LMNA (0.32) ALDH1A1POLBHPGDTSHRHTT
SCHEMBL6751624 0.67 LMNA (0.31) ALDH1A1POLBHPGDTSHRHTT
SCHEMBL6708538 0.66 KDM4E (0.32) ALDH1A1MAPTKDM4EMEN1POLB
SCHEMBL924270 0.65 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRHTT
SCHEMBL27956089 0.65 POLB (0.38) ALDH1A1POLBHSD17B10TSHR
SCHEMBL20658065 0.63 GABRA1 (0.38) HPGDTSHR
SCHEMBL27702827 0.63 GABRA1 (0.31)
SCHEMBL29671489 0.63 LMNA (0.31) ALDH1A1POLBHPGDTSHRHTT
SCHEMBL5573258 0.63 LMNA (0.31) ALDH1A1POLBHPGDTSHRHTT
SCHEMBL6697302 0.62 ALDH1A1 (0.38) ALDH1A1MAPTKDM4EMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179025-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME Cryovac, Inc. (US) 2002-02-13 EP disclosed
EP-1171481-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME Cryovac, Inc. (US) 2002-01-16 EP disclosed
US-6197714-B1 USEFUL IN SLURRY AND GAS PHASE POLYMERIZATION OF OLEFINS CRYOVAC, INC. 2001-03-06 US disclosed
US-6197715-B1 USEFUL IN SLURRY AND GAS PHASE POLYMERIZATION OF OLEFINS CRYOVAC, INC. 2001-03-06 US disclosed
WO-2000056786-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME CRYOVAC, INC. (US) 2000-09-28 WO disclosed
WO-2000056787-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME CRYOVAC, INC. (US) 2000-09-28 WO disclosed