Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 11/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686342 | 0.74 | DRD2 (0.46) | STSDRD2 | |
| SCHEMBL5468373 | 0.71 | SLC6A2 (0.48) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL3236376 | 0.67 | HTR2A (0.46) | STSHTR2ADRD2SLC6A2HTR2C | |
| SCHEMBL11213212 | 0.66 | S1PR3 (0.62) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11210990 | 0.65 | S1PR3 (0.64) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL12629837 | 0.64 | HTR2A (0.47) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11206938 | 0.64 | S1PR3 (0.69) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL12629835 | 0.64 | SPHK1 (0.47) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL12629840 | 0.64 | SPHK1 (0.47) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL12629841 | 0.64 | SPHK1 (0.47) | HTR2ADRD2SLC6A2HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049348-A1 | For use in nematic or cholesteric liquid-crystal mixtures which have positive dielectric anisotropy values; broad operating temperature range and low threshold voltage (for use in automobiles, portable devices-telephones, computers) | MERCK PATENT GMBH | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049348-A1 | For use in nematic or cholesteric liquid-crystal mixtures which have positive dielectric anisotropy values; broad operating temperature range and low threshold voltage (for use in automobiles, portable devices-telephones, computers) | NCS1, HCN1, CACNA1I | STS 4008/4885HTR2A 2137/4885DRD2 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.