Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530691 | 0.76 | LPAR1 (0.49) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL1758545 | 0.76 | KMT2A (0.57) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL7530972 | 0.74 | KDM4E (0.53) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4466528 | 0.73 | SMN1; SMN2 (0.51) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL4324973 | 0.73 | KDM4E (0.68) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL16609990 | 0.72 | GAA (0.68) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8118521 | 0.71 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL2203557 | 0.70 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTGAALMNA | |
| SCHEMBL1758610 | 0.70 | KMT2A (0.53) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL1758833 | 0.70 | ACHE (0.50) | ALDH1A1KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| US-4140860-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4119668-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4085144-A | ANTIBACTERIAL | STERLING DRUG INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4022833-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1977-05-10 | — | — | US | disclosed |