Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531295 | 1.00 | GRM2 (0.46) | GRM2LMNAPOLBALDH1A1HDAC1 | |
| SCHEMBL176708 | 0.83 | GRM2 (0.41) | GRM2LMNAPOLBALDH1A1HDAC1 | |
| SCHEMBL176707 | 0.83 | GRM2 (0.41) | GRM2LMNAPOLBALDH1A1HDAC1 | |
| SCHEMBL7528419 | 0.82 | ALDH1A1 (0.37) | GRM2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL7531409 | 0.82 | ALDH1A1 (0.37) | GRM2ALDH1A1GAA | |
| SCHEMBL7528415 | 0.82 | ALDH1A1 (0.37) | GRM2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL7531404 | 0.82 | ALDH1A1 (0.37) | GRM2ALDH1A1GAA | |
| SCHEMBL7530567 | 0.80 | L3MBTL1 (0.38) | GRM2ALDH1A1 | |
| SCHEMBL7530324 | 0.80 | L3MBTL1 (0.38) | GRM2ALDH1A1 | |
| SCHEMBL7526398 | 0.74 | GRM2 (0.51) | GRM2LMNAPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1195371-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-04-10 | — | — | EP | disclosed |