Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528415 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TRPM8TP53POLBL3MBTL1 | |
| SCHEMBL7531409 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TRPM8L3MBTL1GRM2 | |
| SCHEMBL7531404 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TRPM8L3MBTL1GRM2 | |
| SCHEMBL7530567 | 0.85 | L3MBTL1 (0.38) | ALDH1A1L3MBTL1GRM2 | |
| SCHEMBL7530324 | 0.85 | L3MBTL1 (0.38) | ALDH1A1L3MBTL1GRM2 | |
| SCHEMBL7531295 | 0.82 | GRM2 (0.46) | ALDH1A1POLBMEN1KMT2AGRM2 | |
| SCHEMBL7531291 | 0.82 | GRM2 (0.46) | ALDH1A1POLBMEN1KMT2AGRM2 | |
| SCHEMBL178182 | 0.75 | KCNH2 (0.36) | ALDH1A1TRPM8POLBMEN1KMT2A | |
| SCHEMBL27555237 | 0.75 | MEN1 (0.44) | ALDH1A1TP53POLBL3MBTL1MEN1 | |
| SCHEMBL7533145 | 0.74 | MEN1 (0.46) | ALDH1A1TP53POLBL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1195371-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-04-10 | — | — | EP | disclosed |