Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198772 | 0.85 | KCNH2 (0.74) | KCNH2SLC10A6CCR2KMT2ALMNA | |
| SCHEMBL2158425 | 0.83 | ACLY (0.54) | ACLYKCNH2SLC10A6KMT2AMEN1 | |
| SCHEMBL7537156 | 0.82 | EDNRA (0.51) | ACLYKCNH2SLC10A6CCR2KMT2A | |
| SCHEMBL532975 | 0.81 | ACLY (0.69) | ACLYKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL2748631 | 0.80 | KCNH2 (0.60) | ACLYKCNH2SLC10A6CCR2KMT2A | |
| Hydrochloric Acid SCHEMBL533067 | 0.80 | ACLY (0.68) | ACLYKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL7532769 | 0.80 | MAPT (0.53) | ACLYKCNH2SLC10A6CCR2KMT2A | |
| SCHEMBL7533735 | 0.80 | KMT2A (0.49) | ACLYKCNH2SLC10A6CCR2KMT2A | |
| SCHEMBL28363356 | 0.79 | CCR2 (0.51) | ACLYCCR2KDM4ETSHRALDH1A1 | |
| SCHEMBL4569871 | 0.78 | ACLY (0.52) | ACLYKCNH2SLC10A6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |