Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533735 | 0.89 | KMT2A (0.49) | MAPTKCNH2RAB9ACCR2LMNA | |
| SCHEMBL7538991 | 0.88 | HTT (0.51) | MAPTKCNH2NPC1RAB9ACCR2 | |
| SCHEMBL7533748 | 0.88 | CCR2 (0.53) | MAPTKCNH2NPC1RAB9ACCR2 | |
| SCHEMBL7537204 | 0.88 | MAPT (0.51) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7537156 | 0.87 | EDNRA (0.51) | KCNH2CCR2LMNAKMT2ATDP1 | |
| SCHEMBL7538052 | 0.83 | SMN1; SMN2 (0.56) | MAPTKCNH2NPC1RAB9ALMNA | |
| SCHEMBL7563545 | 0.83 | CCR2 (0.48) | MAPTKCNH2NPC1RAB9ACCR2 | |
| SCHEMBL7532539 | 0.80 | LMNA (0.53) | MAPTKCNH2LMNAKMT2ASLC10A6 | |
| SCHEMBL7531342 | 0.80 | ACLY (0.54) | KCNH2CCR2LMNAKMT2ATDP1 | |
| SCHEMBL7530740 | 0.79 | MEN1 (0.50) | MAPTKCNH2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |