Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7531671 | 0.99 | ACLY (0.66) | ACLYTSHRLMNAHPGDKCNH2 | |
| SCHEMBL7531669 | 0.88 | ACLY (0.55) | ACLYTSHRLMNAHPGDKCNH2 | |
| SCHEMBL7533945 | 0.86 | HPGD (0.69) | ACLYTSHRLMNAHPGDKCNH2 | |
| SCHEMBL7531850 | 0.82 | ACLY (0.46) | ACLYTSHRLMNAHPGDKCNH2 | |
| SCHEMBL7530740 | 0.82 | MEN1 (0.50) | ACLYTSHRLMNAHPGDKCNH2 | |
| SCHEMBL492007 | 0.82 | ACLY (0.77) | ACLYTSHRLMNAHPGDALDH1A1 | |
| SCHEMBL7537385 | 0.81 | ACLY (0.51) | ACLYTSHRLMNAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL492324 | 0.81 | ACLY (0.75) | ACLYTSHRLMNAHPGDALDH1A1 | |
| SCHEMBL21930877 | 0.81 | ACLY (1.00) | ACLYTSHRLMNAHPGDKMT2A | |
| SCHEMBL2747035 | 0.80 | ACLY (0.62) | ACLYTSHRLMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |