Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | FLT1 | P17948 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537385 | 0.92 | ACLY (0.51) | MEN1KMT2AMAPTHTTGRM4 | |
| SCHEMBL7531845 | 0.91 | HTT (0.47) | MEN1KMT2AMAPTHTTGRM4 | |
| SCHEMBL7531850 | 0.91 | ACLY (0.46) | MEN1KMT2AMAPTHTTGRM4 | |
| SCHEMBL7532791 | 0.89 | MEN1 (0.49) | MEN1KMT2AMAPTACLYALDH1A1 | |
| SCHEMBL7531372 | 0.88 | SLC10A2 (0.48) | MEN1KMT2AMAPTGRM4KCNH2 | |
| SCHEMBL7531761 | 0.87 | MAPT (0.49) | MEN1KMT2AMAPTHTTGRM4 | |
| SCHEMBL7535071 | 0.87 | LMNA (0.47) | MEN1KMT2AMAPTHTTKCNH2 | |
| SCHEMBL7534822 | 0.85 | HTT (0.51) | MEN1KMT2AMAPTHTTACLY | |
| SCHEMBL7568445 | 0.85 | MEN1 (0.53) | MEN1KMT2AMAPTHTTGRM4 | |
| SCHEMBL7533629 | 0.84 | LMNA (0.51) | MEN1KMT2AMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |