Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21635272 | 0.80 | SMN1; SMN2 (0.38) | TAAR1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL28586881 | 0.78 | CTSK (0.44) | TSHRALDH1A1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL631905 | 0.76 | TAAR1 (0.75) | TAAR1 | |
| SCHEMBL7844346 | 0.76 | TAAR1 (0.58) | TAAR1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL22032542 | 0.74 | CHRM2 (0.46) | TSHRADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL5533157 | 0.71 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1HPGDPTGES | |
| SCHEMBL22032505 | 0.71 | CHRM2 (0.42) | TSHRMEN1KMT2AALDH1A1ADRA2B | |
| SCHEMBL14813400 | 0.71 | KMT2A (0.40) | TSHRMEN1KMT2AALDH1A1ADRA2B | |
| SCHEMBL6632726 | 0.71 | HTR7 (0.42) | TAAR1HTR2A | |
| SCHEMBL627250 | 0.70 | TAAR1 (0.53) | TAAR1TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020107391-A1 | Process for the synthesis of an endothelin receptor antagonist | FREY LISA F (US) | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107391-A1 | Process for the synthesis of an endothelin receptor antagonist | EDNRA, EDNRB, AGTR2 | TAAR1 179/4885TSHR 167/4885MEN1 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.