SCHEMBL753158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755739	0.91	PTGER1 (0.38)	PTGER1SMN1; SMN2MAPTL3MBTL1POLB
	SCHEMBL16921615	0.91	PTGER1 (0.38)	PTGER1SMN1; SMN2MAPTL3MBTL1POLB
	SCHEMBL754394	0.88	MAPT (0.36)	PTGER1SMN1; SMN2MAPTL3MBTL1POLB
	SCHEMBL16921611	0.88	MAPT (0.36)	PTGER1SMN1; SMN2MAPTL3MBTL1POLB
	SCHEMBL752918	0.88	MAPT (0.43)	PTGER1SMN1; SMN2MAPTL3MBTL1POLB
	SCHEMBL16921603	0.87	SMN1; SMN2 (0.43)	PTGER1SMN1; SMN2MAPTL3MBTL1POLB
	SCHEMBL751907	0.87	PTGER1 (0.40)	PTGER1SMN1; SMN2MAPTL3MBTL1POLB
	SCHEMBL16921609	0.86	LOXL2 (0.44)	PTGER1SMN1; SMN2MAPTL3MBTL1POLB
	SCHEMBL18590778	0.86	ALDH1A1 (0.37)	PTGER1SMN1; SMN2MAPTPOLBMAOA
	SCHEMBL753257	0.85	SMN1; SMN2 (0.39)	PTGER1SMN1; SMN2MAPTL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.