SCHEMBL752918

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Benzylamine SCHEMBL752164	0.95	MAPT (0.40)	MAPTL3MBTL1POLBTDP1PTGER1
	SCHEMBL752163	0.91	LMNA (0.48)	MAPTL3MBTL1POLBKMT2ALMNA
	SCHEMBL753517	0.90	KMT2A (0.42)	POLBPTGER1KMT2ASMN1; SMN2LMNA
	SCHEMBL16921603	0.89	SMN1; SMN2 (0.43)	MAPTL3MBTL1POLBTDP1PTGER1
	SCHEMBL751907	0.89	PTGER1 (0.40)	MAPTL3MBTL1POLBTDP1PTGER1
	SCHEMBL16921609	0.88	LOXL2 (0.44)	MAPTL3MBTL1POLBTDP1PTGER1
	SCHEMBL753158	0.88	PTGER1 (0.40)	MAPTL3MBTL1POLBTDP1PTGER1
	SCHEMBL753257	0.87	SMN1; SMN2 (0.39)	MAPTL3MBTL1POLBTDP1PTGER1
	SCHEMBL16921610	0.87	SMN1; SMN2 (0.37)	MAPTL3MBTL1POLBTDP1PTGER1
	SCHEMBL752400	0.86	PTGER1 (0.39)	MAPTL3MBTL1POLBTDP1PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.