Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.68 |
| ▸ | HTR3A | P46098 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27783041 | 0.98 | MAOA (0.66) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL7483683 | 0.94 | MAOA (0.61) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL194508 | 0.87 | CYP4F2 (0.63) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL2888716 | 0.84 | TSHR (0.60) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL522136 | 0.83 | KMT2A (0.59) | CYP1A2ALDH1A1ALOX15KMT2AMAPT | |
| SCHEMBL9827284 | 0.83 | BAZ2B (0.58) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL754826 | 0.83 | LMNA (0.62) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL29375324 | 0.83 | ALDH1A1 (0.64) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL2132644 | 0.83 | ALDH1A1 (0.64) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL6705158 | 0.83 | CHRM2 (0.59) | MAOACHRM2CHRM3HTR2CCHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199572-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING TYPE 2 DIABETES AND DEMENTIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-06-20 | — | — | US | disclosed |
| EP-4308554-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING TYPE 2 DIABETES AND DEMENTIA | The Board of Trustees of the University of Illinois (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022197658-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING TYPE 2 DIABETES AND DEMENTIA | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-09-22 | — | — | WO | disclosed |
| CN-103502216-B | As pesticide and acaricidal indole carboxamides and benzimidazole-carboxamide | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-04 | — | — | CN | disclosed |
| CN-102741222-B | Haloalkyl-substituted amides as insecticides and acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-02 | — | — | CN | disclosed |
| US-9107411-B2 | Indolecarboxamides and benzimidazolecarboxamides as insecticides and acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-18 | — | — | US | disclosed |
| EP-2683688-B1 | INDOLECARBOXAMIDES AND BENZIMIDAZOLECARBOXAMIDES AS INSECTICIDES AND ACARICIDES | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | disclosed |
| EP-0800524-A1 | 6- TRIAZOLYL 3-(TRIFLUOROMETHYL)PHENYL]METHYL]-2-QUINOLINONES AND -QUINOLINETHIONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-10-15 | — | — | EP | disclosed |
| US-5675024-A | RETINOID RECEPTOR AGONISTS | ALLERGAN (US) | 1997-10-07 | — | — | US | disclosed |
| WO-1997019052-A1 | ARYL OR HETEROARYL AMIDES OF TETRAHYDRONAPHTHALENE, CHROMAN, THIOCHROMAN AND 1,2,3,4-TETRAHYDROQUINOLINE CARBOXYLIC ACIDS HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1997-05-29 | — | — | WO | disclosed |
| WO-1996020200-A1 | 6-[TRIAZOLYL[3-(TRIFLUOROMETHYL)PHENYL]METHYL]-2-QUINOLINONES AND -QUINOLINETHIONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-07-04 | — | — | WO | disclosed |
| US-5347052-A | Preparation of 3,5-diaminobenzotrifluoride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5144076-A | Preparation of 3,5-diamino benzotrifluoride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0484767-A1 | Preparation of 3,5-diamino benzotrifluoride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| EP-0106060-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-09-28 | — | — | EP | disclosed |
| US-4562199-A | ANTICOAGULANTS | WELLCOME FOUNDATION LIMITED, A CORP OF ENGLAND (GB) | 1985-12-31 | — | — | US | disclosed |
| EP-0106060-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199572-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING TYPE 2 DIABETES AND DEMENTIA | SREBF2, SREBF1, SLC2A2 | MAOA 2046/4885CHRM2 663/4885CHRM3 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.