Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.58 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | USP8 | P40818 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SCD | O00767 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533299 | 0.97 | CASP3 (0.61) | CASP3SENP8SENP7SENP6USP2 | |
| SCHEMBL7530791 | 0.82 | POLB (0.56) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7534428 | 0.80 | KMT2A (0.53) | MEN1KMT2AALDH1A1MAPK1ACLY | |
| SCHEMBL532975 | 0.80 | ACLY (0.69) | MEN1KMT2AALDH1A1ACLY | |
| Hydrochloric Acid SCHEMBL533067 | 0.78 | ACLY (0.68) | MEN1KMT2AALDH1A1ACLY | |
| SCHEMBL7531142 | 0.78 | POLB (0.59) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7534349 | 0.76 | ACLY (0.53) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL7532807 | 0.75 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7537224 | 0.75 | ACLY (0.47) | MEN1KMT2AALDH1A1ACLY | |
| SCHEMBL617744 | 0.74 | ALDH1A1 (0.72) | CASP3SENP8SENP7SENP6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |