Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.62 |
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537056 | 0.78 | ACLY (0.43) | ALDH1A1HSD17B10MAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL7533299 | 0.77 | CASP3 (0.61) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7531142 | 0.75 | POLB (0.59) | NPC1RAB9AALDH1A1HSD17B10MAPK1 | |
| SCHEMBL7531704 | 0.75 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL7532067 | 0.75 | CASP3 (0.58) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7569455 | 0.74 | KDM4E (0.67) | NPC1RAB9AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7531707 | 0.74 | RECQL (0.60) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7531331 | 0.74 | DHODH (0.55) | ALDH1A1MAPK1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL7531380 | 0.74 | HTT (0.52) | ALDH1A1SMN1; SMN2KDM4ENPSR1MEN1 | |
| SCHEMBL7566310 | 0.73 | GRM4 (0.41) | ALDH1A1MAPK1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |