Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373550 | 0.95 | ALDH1A1 (0.41) | ALDH1A1MAOAMAOBGAAL3MBTL1 | |
| SCHEMBL27767907 | 0.79 | MAOA (0.40) | ALDH1A1MAOAMAOBGAATSHR | |
| SCHEMBL28015460 | 0.79 | MAOA (0.44) | ALDH1A1MAOAMAOBGAAL3MBTL1 | |
| SCHEMBL156160 | 0.79 | MAOA (0.54) | ALDH1A1MAOAMAOBGAAPOLB | |
| SCHEMBL8347115 | 0.79 | MAOA (0.54) | ALDH1A1MAOAMAOBGAAPOLB | |
| SCHEMBL28001928 | 0.78 | MAOA (0.39) | ALDH1A1MAOAMAOBGAAL3MBTL1 | |
| SCHEMBL31672689 | 0.78 | L3MBTL1 (0.46) | ALDH1A1MAOAMAOBGAAL3MBTL1 | |
| SCHEMBL28001926 | 0.78 | MAOA (0.39) | ALDH1A1MAOAMAOBGAALMNA | |
| SCHEMBL4581280 | 0.77 | MAOA (0.52) | ALDH1A1MAOAMAOBGAAPOLB | |
| SCHEMBL1588016 | 0.77 | MAOA (0.52) | ALDH1A1MAOAMAOBGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030897-A2 | COMPOSITIONS AND METHODS FOR REGULATING THE NERVOUS SYSTEM | FILLION GILLES (FR) | 2002-04-18 | — | — | WO | disclosed |