Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31672689 | 0.81 | L3MBTL1 (0.46) | MAOAMAOBALDH1A1POLBUSP2 | |
| SCHEMBL7532162 | 0.79 | ALDH1A1 (0.41) | MAOAMAOBOPRL1OPRM1ALDH1A1 | |
| SCHEMBL28015460 | 0.79 | MAOA (0.44) | MAOAMAOBOPRL1OPRM1ALDH1A1 | |
| SCHEMBL8347115 | 0.79 | MAOA (0.54) | MAOAMAOBOPRL1OPRM1ALDH1A1 | |
| SCHEMBL156160 | 0.79 | MAOA (0.54) | MAOAMAOBOPRL1OPRM1ALDH1A1 | |
| SCHEMBL7695086 | 0.79 | DPP4 (0.39) | MAOAMAOBOPRL1OPRM1GAA | |
| SCHEMBL28001926 | 0.78 | MAOA (0.39) | MAOAMAOBOPRL1OPRM1ALDH1A1 | |
| SCHEMBL28001928 | 0.78 | MAOA (0.39) | MAOAMAOBOPRL1OPRM1ALDH1A1 | |
| SCHEMBL4581280 | 0.77 | MAOA (0.52) | MAOAMAOBOPRL1OPRM1ALDH1A1 | |
| SCHEMBL1588016 | 0.77 | MAOA (0.52) | MAOAMAOBOPRL1OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101560167-A | Alpha-n-methylation of amino acids | HOFFMANN LA ROCHE (CH) | 2009-10-21 | — | — | CN | claimed |
| CN-101560167-A | Alpha-n-methylation of amino acids | HOFFMANN LA ROCHE (CH) | 2009-10-21 | — | — | CN | disclosed |