SCHEMBL7532422

SCHEMBL7532422

N#Cc1ccccc1N1CCN(CCCCc2c[nH]c3ccccc23)CC1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 4/20 0.65
DRD2 P14416 8/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7530336 0.89 HTR1A (0.73) HTR1ADRD2
SCHEMBL9696701 0.88 DRD2 (0.52) HTR1ADRD2
Hydrochloric Acid SCHEMBL27447154 0.88 HTR1A (0.71) HTR1ADRD2
SCHEMBL7956882 0.85 HTR1A (0.68) HTR1ADRD2
SCHEMBL6925730 0.85 HTR1A (0.70) HTR1ADRD2
SCHEMBL7538925 0.83 DRD2 (0.68) HTR1ADRD2
SCHEMBL7532686 0.83 DRD2 (0.59) HTR1ADRD2
SCHEMBL9699040 0.82 HTR1A (0.59) HTR1A
SCHEMBL9260348 0.81 HTR1A (0.53) HTR1ADRD2
SCHEMBL11824808 0.81 HTR1A (0.76) HTR1ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002030422-A1 USE OF DEFINED SUBSTANCES THAT BIND TO THE SIGMA RECEPTOR FOR COMBATING SARCOMA AND CARCINOMA MERCK PATENT GMBH (DE) 2002-04-18 WO disclosed
WO-2002030422-A1 USE OF DEFINED SUBSTANCES THAT BIND TO THE SIGMA RECEPTOR FOR COMBATING SARCOMA AND CARCINOMA MERCK PATENT GMBH (DE) 2002-04-18 WO disclosed