Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532422 | 0.88 | HTR1A (0.65) | DRD2HTR1A | |
| SCHEMBL7530336 | 0.81 | HTR1A (0.73) | DRD2HTR1AHTR2AHTR6KCNH2 | |
| Hydrochloric Acid SCHEMBL27447154 | 0.81 | HTR1A (0.71) | DRD2HTR1AHTR2AHTR6KCNH2 | |
| SCHEMBL26508416 | 0.79 | HTR2A (0.66) | HTR1AHTR2AHTR6 | |
| SCHEMBL7956882 | 0.78 | HTR1A (0.68) | DRD2HTR1AHTR2AHTR6KCNH2 | |
| SCHEMBL7532686 | 0.77 | DRD2 (0.59) | DRD2HTR1AHTR2AHTR6KCNH2 | |
| SCHEMBL7534426 | 0.77 | DRD2 (0.56) | DRD2HTR1AHTR2AHTR6KCNH2 | |
| SCHEMBL9461302 | 0.76 | HTR1A (0.60) | DRD2HTR1A | |
| SCHEMBL9699040 | 0.76 | HTR1A (0.59) | HTR1AHTR6KCNH2 | |
| SCHEMBL9260348 | 0.75 | HTR1A (0.53) | DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496222-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |