Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9258224 | 0.87 | MPO (0.61) | — | |
| SCHEMBL9266153 | 0.86 | MPO (0.62) | — | |
| SCHEMBL7530336 | 0.83 | HTR1A (0.73) | HTR1ADRD2HTR2A | |
| SCHEMBL9699040 | 0.82 | HTR1A (0.59) | HTR1A | |
| Hydrochloric Acid SCHEMBL27447154 | 0.82 | HTR1A (0.71) | HTR1ADRD2HTR2A | |
| SCHEMBL7532422 | 0.81 | HTR1A (0.65) | HTR1ADRD2 | |
| SCHEMBL7956882 | 0.80 | HTR1A (0.68) | HTR1ADRD2HTR2A | |
| SCHEMBL9282707 | 0.78 | HTR6 (0.52) | — | |
| SCHEMBL9696701 | 0.75 | DRD2 (0.52) | HTR1ADRD2HTR2A | |
| SCHEMBL9265740 | 0.74 | ADRA2A (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418237-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-05-23 | — | — | US | disclosed |