Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530786 | 0.88 | LTA4H (0.45) | KMT2AMEN1FFAR4FFAR1CA1 | |
| SCHEMBL7533057 | 0.87 | KMT2A (0.50) | GAAKMT2AMEN1FFAR4 | |
| SCHEMBL3940302 | 0.81 | KMT2A (0.59) | ALOX5OR51E2KMT2AMEN1CA1 | |
| SCHEMBL7530218 | 0.79 | HMGCR (0.41) | TRPV1KMT2AMEN1HMGCR | |
| SCHEMBL28287006 | 0.79 | CYP19A1 (0.65) | ALOX5OR51E2CYP19A1TRPV1GAA | |
| Dihydroferulic Acid Methyl Ester SCHEMBL490876 | 0.79 | ALOX5 (0.77) | ALOX5OR51E2TRPV1GAA | |
| SCHEMBL21494459 | 0.78 | PDE4D (0.59) | ALOX5OR51E2KMT2AMEN1 | |
| SCHEMBL7532062 | 0.76 | FFAR1 (0.54) | KMT2AMEN1FFAR4FFAR1APP | |
| SCHEMBL8959275 | 0.76 | HMGCR (0.41) | TRPV1FFAR4FFAR1HMGCR | |
| SCHEMBL18224202 | 0.75 | ALOX5 (0.54) | ALOX5OR51E2KMT2AMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585371-B1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INTERNAT H (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0585371-A4 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INT (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0585371-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020350-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | disclosed |