Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533057 | 0.90 | KMT2A (0.50) | FFAR4MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL347209 | 0.79 | FFAR4 (0.61) | FFAR1FFAR4MEN1KMT2APLA2G4A | |
| Hydrochloric Acid SCHEMBL3225386 | 0.78 | FFAR4 (0.59) | FFAR1FFAR4MEN1KMT2APLA2G4A | |
| SCHEMBL7529980 | 0.77 | POLB (0.43) | POLBHSD17B10MTNR1AMTNR1B | |
| Azelaic Acid SCHEMBL8684597 | 0.77 | HSD17B10 (0.65) | POLBMEN1KMT2AHSD17B10PLA2G4A | |
| SCHEMBL7822529 | 0.77 | FFAR4 (0.73) | FFAR1FFAR4KMT2AMTNR1AMTNR1B | |
| SCHEMBL7531680 | 0.77 | FFAR4 (0.47) | FFAR1FFAR4POLBFFAR2 | |
| SCHEMBL7535383 | 0.76 | MTNR1B (0.42) | POLBMEN1KMT2AHSD17B10MTNR1A | |
| SCHEMBL7532476 | 0.76 | ALOX5 (0.50) | FFAR1FFAR4MEN1KMT2AAPP | |
| SCHEMBL491188 | 0.76 | HSD17B10 (0.71) | POLBMEN1KMT2AHSD17B10MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | claimed |
| EP-0585371-A4 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INT (US) | 1994-07-13 | — | — | EP | claimed |
| EP-0585371-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-09 | — | — | EP | claimed |
| WO-1992020350-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | claimed |
| EP-0585371-B1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INTERNAT H (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0585371-A4 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INT (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0585371-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020350-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | disclosed |