Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7532719

CC[C@H]1c2nc[nH]c2C[C@@H](C(=O)NCC(C)C)N1C(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
AOC3 Q16853 1/20 0.31
XIAP P98170 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7532721 0.86 AOC3 (0.32) SMN1; SMN2AOC3
Trifluoroacetic Acid SCHEMBL7531136 0.83 KDM4E (0.33) HRH4HRH3SMN1; SMN2KDM4EALDH1A1
SCHEMBL7541001 0.70 MMP8 (0.34) HRH4HRH3SMN1; SMN2AOC3KDM4E
Trifluoroacetic Acid SCHEMBL7572001 0.70 AOC3 (0.43) HRH4HRH3AOC3KDM4EALDH1A1
SCHEMBL7531140 0.69
SCHEMBL3249168 0.67 AOC3 (0.43) SMN1; SMN2AOC3KDM4EALDH1A1GAA
SCHEMBL12094891 0.67 AOC3 (0.43) SMN1; SMN2AOC3KDM4EALDH1A1GAA
SCHEMBL3249047 0.67 AOC3 (0.43) SMN1; SMN2AOC3KDM4EALDH1A1GAA
Trifluoroacetic Acid SCHEMBL7530146 0.67 AOC3 (0.45) HRH4HRH3AOC3ALDH1A1
SCHEMBL12094877 0.65 AOC3 (0.42) SMN1; SMN2AOC3KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020198189-A1 Treatment or prophylaxis of Semicarbazide-sensitive amine oxidase (SSAO) mediated complications in mammals including humans BIOVITRUM AB (SE) 2002-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020198189-A1 Treatment or prophylaxis of Semicarbazide-sensitive amine oxidase (SSAO) mediated complications in mammals including humans AOC3, AOC2, AOC1 HRH4 148/4885HRH3 77/4885SMN1; SMN2 217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.