Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703648 | 0.83 | RAB9A (0.56) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL633920 | 0.82 | RAB9A (0.59) | HTTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1703428 | 0.82 | DHODH (0.51) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL1703768 | 0.81 | RAB9A (0.64) | HTTGRM4NPC1RAB9AMEN1 | |
| SCHEMBL890809 | 0.81 | MAPT (0.55) | HTTGRM4MEN1MAPTKMT2A | |
| SCHEMBL890859 | 0.75 | GCK (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19NPC1 | |
| SCHEMBL472983 | 0.75 | FADS1 (0.78) | FADS1HTTGRM4NPC1RAB9A | |
| SCHEMBL2529744 | 0.75 | LMNA (0.69) | HTTNPC1RAB9AMEN1MAPT | |
| SCHEMBL29406000 | 0.75 | FADS1 (0.78) | FADS1HTTGRM4NPC1RAB9A | |
| SCHEMBL1703430 | 0.75 | RXFP1 (0.44) | L3MBTL1NPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |