SCHEMBL753320

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752036	0.85	SIGMAR1 (0.45)	SIGMAR1HTR7MAP2K7MAPK1KCNH2
	SCHEMBL755313	0.80	TAAR1 (0.58)	SIGMAR1MAP2K7MAPK1KCNH2EGFR
	SCHEMBL19334491	0.79	SIGMAR1 (0.58)	SIGMAR1LMNAATMTAAR1
	SCHEMBL13754947	0.79	KCNH2 (0.56)	MAP2K7MAPK1KCNH2EGFRLMNA
	SCHEMBL3432650	0.77	MAP2K7 (0.44)	MAP2K7MAPK1KCNH2EGFRLMNA
	SCHEMBL755006	0.77	MAP2K7 (0.40)	HTR7MAP2K7MAPK1KCNH2EGFR
	SCHEMBL757063	0.76	L3MBTL1 (0.58)	HTR7MAP2K7MAPK1KCNH2EGFR
	SCHEMBL752175	0.76	GAA (0.58)	SIGMAR1KCNH2ESR1
	SCHEMBL752022	0.73	MAP2K7 (0.40)	HTR7MAP2K7MAPK1KCNH2EGFR
	SCHEMBL13754981	0.72	KCNH2 (0.47)	MAP2K7MAPK1KCNH2EGFRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.