SCHEMBL755313

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13754947	0.86	KCNH2 (0.56)	TAAR1LMNAALDH1A1ALOX15KCNH2
	SCHEMBL3432650	0.83	MAP2K7 (0.44)	LMNAALDH1A1MEN1KMT2AKCNH2
	SCHEMBL752036	0.83	SIGMAR1 (0.45)	LMNASIGMAR1KCNH2MAPK1EGFR
	SCHEMBL755006	0.83	MAP2K7 (0.40)	TAAR1ATMLMNAALDH1A1MEN1
	SCHEMBL757063	0.82	L3MBTL1 (0.58)	TAAR1LMNAALDH1A1L3MBTL1MEN1
	SCHEMBL752175	0.82	GAA (0.58)	ALDH1A1MEN1KMT2ASIGMAR1KCNH2
	SCHEMBL753320	0.80	SIGMAR1 (0.41)	TAAR1ATMLMNASIGMAR1KCNH2
	SCHEMBL752022	0.79	MAP2K7 (0.40)	TAAR1ATMLMNAKCNH2MAPK1
	SCHEMBL13754981	0.77	KCNH2 (0.47)	LMNAKCNH2MAPK1EGFRAPP
	SCHEMBL6810696	0.77	HTR2A (0.54)	TAAR1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.