Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GFRA2 | O00451 | 1/20 | 0.37 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533620 | 0.79 | IDO1 (0.46) | GPR84IDO1HTR2ATAAR1 | |
| SCHEMBL7258599 | 0.72 | IDO1 (0.63) | GPR84IDO1HTR2A | |
| SCHEMBL7533615 | 0.72 | IDO1 (0.38) | GPR84IDO1GFRA2GFRA3 | |
| SCHEMBL7425987 | 0.71 | SMPD1 (0.47) | IDO1 | |
| SCHEMBL2206248 | 0.71 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL1745124 | 0.70 | GFRA3 (0.52) | GFRA2GFRA3 | |
| SCHEMBL7410008 | 0.70 | IDO1 (0.61) | GPR84IDO1HTR2A | |
| SCHEMBL2206195 | 0.69 | CYP4F2 (0.66) | — | |
| SCHEMBL2207165 | 0.69 | MAOA (0.53) | IDO1TAAR1 | |
| SCHEMBL20332570 | 0.69 | KCNA3 (0.53) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874819-A1 | IMIDES AS PDE III, PDE IV AND TNF INHIBITORS | CELGENE CORPORATION (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997023457-A1 | IMIDES AS PDE III, PDE IV AND TNF INHIBITORS | CELGENE CORPORATION (US) | 1997-07-03 | — | — | WO | disclosed |