Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424982 | 0.81 | ALDH1A1 (0.51) | SMPD1ABCB1 | |
| SCHEMBL7425981 | 0.81 | KMT2A (0.47) | KDM4EATMIDO1 | |
| SCHEMBL4637327 | 0.77 | FFAR1 (0.43) | IDO1 | |
| SCHEMBL7324772 | 0.76 | PDE4B (0.55) | KDM4EATM | |
| SCHEMBL2468726 | 0.75 | ATM (0.79) | KDM4EATM | |
| SCHEMBL4637286 | 0.75 | ALDH1A1 (0.51) | IDO1 | |
| SCHEMBL7425979 | 0.74 | NPC1 (0.43) | SMPD1KDM4EIDO1 | |
| SCHEMBL8711349 | 0.73 | HTR2C (0.46) | — | |
| SCHEMBL12394730 | 0.72 | PIN1 (0.43) | KDM4EIDO1 | |
| SCHEMBL7533622 | 0.71 | GPR84 (0.42) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874819-A1 | IMIDES AS PDE III, PDE IV AND TNF INHIBITORS | CELGENE CORPORATION (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997023457-A1 | IMIDES AS PDE III, PDE IV AND TNF INHIBITORS | CELGENE CORPORATION (US) | 1997-07-03 | — | — | WO | disclosed |