Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | NRP1 | O14786 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533711 | 0.90 | LMNA (0.49) | LMNAHPGDTSHRACLYKMT2A | |
| SCHEMBL7533715 | 0.84 | LMNA (0.52) | LMNAHPGDTSHRNRP1KMT2A | |
| SCHEMBL7539018 | 0.83 | LMNA (0.49) | LMNAHPGDTSHRACLYNRP1 | |
| SCHEMBL7538001 | 0.83 | ACLY (0.58) | LMNAHPGDTSHRACLYKMT2A | |
| SCHEMBL532975 | 0.81 | ACLY (0.69) | LMNAHPGDTSHRACLYKMT2A | |
| SCHEMBL7537356 | 0.81 | LMNA (0.47) | LMNAHPGDTSHRACLYNRP1 | |
| Hydrochloric Acid SCHEMBL533067 | 0.80 | ACLY (0.68) | LMNAHPGDTSHRACLYKMT2A | |
| SCHEMBL7531722 | 0.80 | LMNA (0.55) | LMNAHPGDTSHRACLYKMT2A | |
| SCHEMBL7530793 | 0.78 | LMNA (0.80) | LMNAHPGDTSHRACLYKMT2A | |
| Sulfathiazole SCHEMBL7533713 | 0.77 | LMNA (0.67) | LMNATSHRACLYKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |