Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | NRP1 | O14786 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539018 | 0.97 | LMNA (0.49) | LMNATSHRHPGDACLYSMN1; SMN2 | |
| SCHEMBL7537343 | 0.91 | S1PR3 (0.47) | LMNATSHRHPGDACLYSMN1; SMN2 | |
| SCHEMBL7539012 | 0.87 | LMNA (0.47) | LMNATSHRHPGDACLYSMN1; SMN2 | |
| SCHEMBL7537349 | 0.85 | LMNA (0.53) | LMNATSHRHPGDSMN1; SMN2KAT6A | |
| SCHEMBL7539015 | 0.81 | LMNA (0.55) | LMNATSHRHPGDSMN1; SMN2HTT | |
| SCHEMBL7533719 | 0.81 | LMNA (0.51) | LMNATSHRHPGDACLYKAT6A | |
| SCHEMBL7538001 | 0.79 | ACLY (0.58) | LMNATSHRHPGDACLYSMN1; SMN2 | |
| SCHEMBL532975 | 0.77 | ACLY (0.69) | LMNATSHRHPGDACLYHTT | |
| SCHEMBL9191912 | 0.76 | WDR5 (0.68) | LMNATSHRHPGDSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL533067 | 0.76 | ACLY (0.68) | LMNATSHRHPGDACLYHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |