Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CCR9 | P51686 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533719 | 0.90 | LMNA (0.51) | LMNAHPGDTSHRACLYKAT6A | |
| SCHEMBL7539012 | 0.84 | LMNA (0.47) | LMNAHPGDTSHRPARP10ACLY | |
| SCHEMBL7537995 | 0.84 | ACLY (0.56) | LMNAHPGDTSHRPARP10ACLY | |
| SCHEMBL7533715 | 0.82 | LMNA (0.52) | LMNAHPGDTSHRPOLBKAT6A | |
| SCHEMBL7537343 | 0.82 | S1PR3 (0.47) | LMNAHPGDTSHRPARP10ACLY | |
| SCHEMBL532975 | 0.80 | ACLY (0.69) | LMNAHPGDTSHRACLYKMT2A | |
| SCHEMBL7533705 | 0.78 | SCN3A (0.56) | LMNATSHRACLYPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL533067 | 0.78 | ACLY (0.68) | LMNAHPGDTSHRACLYKMT2A | |
| SCHEMBL7537207 | 0.78 | ACLY (0.53) | LMNAHPGDTSHRACLYPOLB | |
| SCHEMBL3657767 | 0.77 | ACLY (0.55) | LMNAHPGDTSHRACLYPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |