Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599207 | 0.89 | ALDH1A1 (0.51) | PPOXGAAPKML3MBTL1TDP1 | |
| SCHEMBL2789871 | 0.87 | GAA (0.55) | PPOXGAAPKML3MBTL1TDP1 | |
| SCHEMBL8603144 | 0.87 | ALDH1A1 (0.62) | PPOXGAAPKML3MBTL1TDP1 | |
| SCHEMBL8598336 | 0.86 | ALDH1A1 (0.57) | PPOXGAAPKML3MBTL1TDP1 | |
| SCHEMBL8603307 | 0.86 | LMNA (0.65) | PPOXGAAL3MBTL1TDP1TSHR | |
| SCHEMBL7561254 | 0.85 | PPOX (0.53) | PPOXGAAPKML3MBTL1TDP1 | |
| SCHEMBL8598863 | 0.82 | TSHR (0.47) | PPOXL3MBTL1TDP1TSHRLMNA | |
| SCHEMBL8598548 | 0.82 | LMNA (0.46) | PPOXL3MBTL1TDP1TSHRLMNA | |
| SCHEMBL8602970 | 0.82 | MAPT (0.46) | PPOXL3MBTL1TDP1TSHRLMNA | |
| SCHEMBL8599627 | 0.81 | PPOX (0.46) | PPOXGAAPKML3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486866-A | Pyrimidine diketone compound and preparation method and application thereof | 贵州大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-113200985-B | Pteridinone compound and preparation method and application thereof | 南开大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-113200985-A | Pteridinone compound and preparation method and application thereof | 南开大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-1262536-C | Production of pyridazine herbicides | SUMITOMO CHEMICAL CO (JP) | 2006-07-05 | — | — | CN | disclosed |
| EP-0934254-B1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-6333413-B1 | PYRIDAZIN-3-ONE DERIVATIVES BY CYCLIZING THE CARBOXY-SUBSTITUTED HYDRAZONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-12-25 | — | — | US | disclosed |
| US-6156891-A | Production of pyridazine herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-05 | — | — | US | disclosed |
| CN-1241175-A | Production of pyridazine herbicides | SUMITOMO CHEMICAL CO (JP) | 2000-01-12 | — | — | CN | disclosed |
| EP-0934254-A1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017632-A1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-30 | — | — | WO | disclosed |
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |